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3. KRAS the most common gene mutation in non-small cell lung cancer (NSCLC) that is oncogenic (driving development of tumors). Using data from the registry of the American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange (GENIE), researchers demonstrated potential differences in the rate of KRASG12C mutations by race. https://www.nejm.org/doi/full/10.1056/NEJMc2030638 Among patients with NSCLC in the GENIE cohort, White and Black patient groups had higher rates of KRASG12C mutations than Asians (White patients, 1153 of 8892 [13%]; Black patients, 94 of 862 [11%]; and Asian patients, 25 of 690 [4%]).
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