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BPA is a chemical of concern because it is an endocrine disruptor and has been associated with various adverse health effects such as heart attacks, coronary heart disease, sexual dysfunction, and immune system alterations. Toxicologists have identified a Reference Dose (RfD) of 5 ngBPA/ kgbodyweight / day and a cancer slope factor of 0.000 000 000 312 5 per ngBPA/ kgbodyweight/ day for use in human health risk assessment Table: BPA concentration in canned and plastic wrapped U.S. Human foods BPA concentration (ngBPA/gfood ) Sample #1 Sample #2 Sample #3 Del Monte Fresh Cut Green Beans 65.00 59.90 26.60 Progresso Light Homestyle Vegetable and Rice Soup 22.70 19.70 15.60 Hormel Chili with Beans 5.59 5.12 3.47 Kroger Mixed Vegetables 4.16 2.30 2.29 Data taken from Schecter et al. Environ. Sci. Technol. 2010, 44, 9425-9430 A 40-year-old man John and his 8-year-old son Johnson are fans of the Progresso Light Homestyle Vegetable and Rice Soup. John started consuming 1 can of the soup (470 g food each can) every day since age 20, and Johnson started consuming half a can of the soup every two days since age 5. Chemical structure of BPA What is the route of exposure to BPA
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HEALTH SCIENCE
NURSING

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