SOLVED1801

A 26-year-old man with a history of schizophrenia is involuntarily admitted to the inpatient psychiatric unit secondary to behavioral decompensation. Collateral information obtained from the patient’s family reveals that the patient was recently started on carbamazepine as an adjunct treatment one week prior to arrival. When asked about the patient’s medication profile before adding the new adjunct, all they can reveal is that he was prescribed an atypical antipsychotic with a potential side effect of QTc prolongation. Which of the following possible drug interactions is most likely responsible for this patient’s acute decompensation? A. Induction of the cytochrome CYP 3A4 enzyme by carbamazepine B. Inhibition of the cytochrome CYP 3A4 enzyme by the atypical antipsychotic C. Induction of the cytochrome CYP 2D6 enzyme by carbamazepine D. Inhibition of the cytochrome CYP 2D6 enzyme by the atypical antipsychotic
SCIENCE
HEALTH SCIENCE
NURSING

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