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An investigator is interested in studying Kaposi’s sarcoma (KS). Her research aim is to assess multiple risk factors for KS at once including HIV status, smoking, lead exposure, occupational lead exposure, severe sunburn history, alcohol use, human papillomavirus, immunosuppression therapy and herpes infections. She is aware that KS is a rare disease and occurs in approximately 47 cases per 1 million people in the United States. Which study design would be most appropriate? Group of answer choices A. Retrospective cohort study of a random sample of adults seeking care at University of Colorado Health System B. Prospective cohort study of all adults seeking care at the University of Colorado Health System with 2 years of follow-up to observe KS incidence. C. Prospective cohort study of all adults seeking care at the University of Colorado Health System with 10 years of follow-up to observe KS incidence. D. Case-control study of KS patients selected from a US cancer registry and controls recruited from primary care, matched by age, sex and county of residence.
SCIENCE
HEALTH SCIENCE
NURSING

 
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