SOLVED1114

The association between use of exogenous and the development of breast cancer among postmenopausal women was studied in the framework of “The Nurses’ Health Study”. The following table presents relevant information from the study: Cigarette smokers Ie = 180 Ie = 420 Non smokers Io = 20 Io = 180 Hormone use Cases of Breast cancer Person-years of follow up Yes 655 137,368 No 923 344,942 4 a. Calculate the relative risk to evaluate the association between exogenous estrogen use and the development of breast cancer for women in this sample. Interpret the result (explain in words to a lay person what the number means). b. Is the number calculated above a rate ratio or a risk ratio? Why? c. If there is a causal relationship between hormone use and breast cancer, how many cases of breast cancer (per 100,000 person-years) could be prevented among hormone user if they did not use hormone? d. If there is a causal relationship between hormone use and breast cancer, how many cases of breast cancer (per 100,000 person-years) could be prevented among the entire cohort if they did not use hormone?
SCIENCE
HEALTH SCIENCE
NURSING

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