SOLVED1083

case: A 58-year-old Bulgarian Caucasian man was referred to a nephrology department due to progressive renal disease. He had no history of hypertension, diabetes, or renal disease. He had one episode of hepatitis at age 38, some GI complaints, and recurrent pulmonary infections. He may have been exposed to ionizing radiation in Ukraine during his childhood. Initial lab results showed mild metabolic acidosis, no electrolyte disturbance, and a moderate elevation of liver enzymes. The hepatic ultrasound and biopsy showed normal liver tissue. The gastric, colonic, and prostate biopsies were all normal. The pulmonary CT scan and function tests were also normal, but the kidney ultrasound showed small kidneys and the biopsy revealed chronic lesions (interstitial fibrosis). The patient was diagnosed with karyomegalic nephritis related to an FAN1 mutation. He later progressed to end-stage kidney disease and was put on peritoneal dialysis as well as on the transplant waitlist. Describe how approaching this case with the emunctories in mind could help the patient, in addition to the treatments provided.
SCIENCE
HEALTH SCIENCE
NURSING

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