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Through evidence and research, there is a strong association between AF and strokes, per Hill’s guidelines. In support of Hill’s experimental guideline, the risks of strokes, systemic embolisms, major bleeding, and death were analyzed using an inverse probability treatment weighted time-dependent Cox regression model. Costs were also compared using marginal structural models. In reviewing the results from the study, “Contemporary clinical and economic outcomes among oral anticoagulant treated and untreated elderly patients with atrial fibrillation: Insights from the United States Medicare database,” the cohort treated with OACs had a lower risk of strokes, systemic emboli, and all-cause death. Though both studies had different approaches, analogy was present as both discussed the use of the same or similar OACs as a treatment for AF. paraphrase
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