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Chapter 22: Drugs for Muscle Spasm and Spasticity • Add the medications discussed to your Prodrug sheets. o Centrally Acting Muscle Relaxer for Spasticity Baclofen (Lioresal, Gablofen) o Centrally Acting Muscle Relaxer for Localized Muscle Spasm Cyclobenzaprine (Amrix, Fexmid) o Direct Acting Muscle Relaxer Dantrolene (Dantrium) • Review Table 22.1. It has a great list of medications and the side effects/ considerations. • Compare and contrast the four drugs—baclofen, diazepam, dantrolene, and tizanidine. • Review all black box warnings and contraindications of these medications.
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