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nurs 6501 nurs 6501 advanced pathophysiology midterm exam: In immune checkpoint myocarditis, a rare but serious complication of cancer immunotherapy, the use of drugs that inhibit CTLA-4 and PD-1 pathways can lead to unintended cardiac effects. What is the primary mechanism by which these drugs contribute to the development of myocarditis? Group of answer choices They stimulate excessive sympathetic nervous system activity, leading to cardiomyocyte apoptosis. They promote an uncontrolled autoimmune response against myocardial antigens. They directly induce cytotoxic effects on cardiomyocytes, leading to necrosis. They decrease myocardial blood flow by inducing coronary artery vasoconstriction.
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