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Spencer et al., 2018 states Potential biases could also be present in TSAs, such as the selection bias and the misclassification bias. A selection bias may occur when study participants differ from the population of interest in the study. This could lead to systematic error by association or outcome. The misclassification bias may occur when the study participants are miscategorized. Thus altering the observed association or research outcome. Some confounders are potentially found in TSAs, such as expired vaccinations or a participant reacting to a vaccination. To alleviate these potential confounders, document each lot number and vaccination expiration date. Participants’ allergies should also be reviewed, verified, and documented before receiving a vaccination. paraphrase
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