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Answer next questions:

The answers must be detailed and cited (APA form).

1. A different type of question…why is respiratory distress rarely the only effect of a venom? Based on what you know about how respiration works mechanically, what other symptoms would likely accompany (in fact, precede) respiratory distress in a victim?

2. The Brown Recluse Spider’s venom can have hemolytic effects. In other words, it lyses RBC’s. Now that you know all about the respiratory system, explain how this reduction of RBC’s would affect oxygen and carbon dioxide transport in the blood. How will these issues be detected? Also explain what mechanisms the body would have to initiate in order to counter the effects beyond making new RBC’s.

3. Many snake venoms contain secretory phospholipases (sPLA2’s) which break down the surfactants in the lungs. Explain how such venoms would lead to respiratory failure. What sorts of changes in the measurements by a spirometer would you see? Which respiratory disease would this most closely mimic?

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