A 62-year-old woman was diagnosed with hypothyroidism and started on levothyroxine replacement thera. Question
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A 62-year-old woman was diagnosed with hypothyroidism and started on levothyroxine replacement therapy. For the previous 8 months, she had been receiving warfarin therapy for the treatment of recurrent deep venous thrombosis. Her warfarin dose was adjusted to maintain her international normalized ratio (INR) between 2 and 3. When she started thyroxine replacement therapy, her physician reduced the dosage of warfarin by 50% and advised her that her INR would need to be monitored on a weekly basis until a new appropriate dose of warfarin was determined. Which of the following statements best explains why the warfarin dose was reduced?
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A 62-year-old woman was diagnosed with hypothyroidism and started on levothyroxine replacement thera