SOLVED4104

You work for a small company trying to develop drugs to treat a variety of neuropsychiatric diseases. Several promising compounds have failed in vivo safety pharmacology tests because they reduced the seizure threshold. Your team has been working on a small molecule for treating generalized anxiety disorder. To avoid additional failures in in vivo safety pharmacology testing, the team decided to explore in vitro methods for assessing seizure liability at an earlier stage of drug discover/develoment. Which experimental model would you support, rat primary cortical cultures or hiPSC neurons? State your Preference and Why?
SCIENCE
HEALTH SCIENCE
NURSING

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