SOLVED3123

response to this post “warfarin inhibits the synthesis of clotting factors II, VII, IX, and X, as well as the naturally occuring endogenous anticoagulant proteins C and S. The anticoagulant and antithrombotic activity of warfarin depends on the clearance of functional clotting factors from the systemic circulation once the drug is administered. The safety and efficacy of warfarin therapy are dependent on maintaining the INR within the target range for the indication.One of the major risks of warfarin therapy is bleeding, which correlates well with INR values. Since warfarin has a narrow therapeutic window and has been associated with many drug-drug and drug-food interactions, patient counselling is essential.
SCIENCE
HEALTH SCIENCE
NURSING

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