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A 40-year-old female patient comes to the office for follow up. She has a 5-year history of HIV treated with ritonavir. She has never had an AIDS defining illness and her most recent CD4 count was 300u/L. 9 months ago, she began experiencing fatigue and her serum creatinine increased from 0.9 mg/dl to 1.4 mg/d and she developed 3g/day proteinuria. A renal biopsy showed that she had HIV associated nephropathy (HIVAN). Abacavir, efavirenz, and lisinopril were initiated and her proteinuria and serum creatinine decreased to 0.3 g/day and 1.1 mg/d respectively. She now presents with nausea and wants to switch back to monotherapy with zidovudine. If she discontinues Highly Active Anti Retroviral Therapy (HAART), she may progress to have what further lab/UA changes?
SCIENCE
HEALTH SCIENCE
NURSING

 
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