SOLVED2336

A 45-year-old patient has been diagnosed with peptic ulcer disease (PUD). The healthcare provider has prescribed amoxicillin in combination with famotidine. What information concerning the medication therapy should be presented to the patient? Rationale: Antibiotics are used in combination with acid-suppressing medications to eradicate H. pylori-induced PUD. Amoxicillin is an aminopenicillin that kills bacteria by interfering with cell wall synthesis. It is most effective at neutral pH levels and, therefore, must be administered with an acid-suppression agent such as a proton pump inhibitor or H2 receptor agonist. It is dosed at 1 gram by mouth twice daily. Famotidine may be taken without regard to meals. A PPI should be taken 30 to 60 meals prior to meals. Page Number and Header 532, Amoxicillin Learning Objective
SCIENCE
HEALTH SCIENCE
NURSING

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