SOLVED2193
Be familiar with what medication instructions the healthcare provider should give the patient being prescribed an antacid that will best facilitate maximum therapeutic results. Antacids have clinically significant drug interactions by altering the rate and extent of absorption of concomitantly administered drugs. The recommendation is to take antacids 1 to 4 hours after other medications to avoid these interactions. Onset of action is about 1 to 2 hours after administration. Therefore, H2RAs may be used as needed or on an intermittent basis for mild heartburn. If there is a lack of response within 2 weeks, standard twice-daily dosing is reasonable. Prolonged use may lead to reduced efficacy or tachyphylaxis and tolerance to the medication; therefore, intermittent use is preferred. Page Number and Header 428, Antacids Learning Objective 2
SCIENCE
HEALTH SCIENCE
NURSING
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