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A 45-year-old man presents for routine physical and laboratory tests. He has a history of diabetes and hypertension. He is obese and is interested in losing weight. The patient denies any past or current use of alcohol or tobacco. On physical exam, vital signs are within normal limits. He has some mild tenderness on palpation in the right upper quadrant. His medications include pioglitazone, hydrochlorothiazide, and metformin. Laboratory examination reveals AST 189U/L, ALT 205U/L, and GGT 75U/L, similar to values 6 months prior. Hepatitis serology is negative. Right upper quadrant ultrasound reveals fatty infiltrates in the liver and no gallstones in the gallbladder. Which of the following is the next step in treating and managing this patient’s disease? A. Discontinue pioglitazone B. Evaluate every 6 months with routine ultrasounds C. Initiate weight-loss management D. Perform a biopsy of the liver to rule out complications
SCIENCE
HEALTH SCIENCE
NURSING

 
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