SOLVED93

ou’re a virologist tasked with developing a vaccine for an outbreak of a virus rapidly spreading through South America, largely in resource limited environments. The virus is transmitted through the fecal-oral route, infects epithelial cells in the colon, and causes severe diarrhea. Infection of infants has caused particular concern. What type of vaccine would you develop (live attenuated, killed, subunit, mRNA, etc) and why? Be sure to include pros and potential cons of the vaccine design you chose. 2. You’re a nurse covering for a short-staffed long-term care facility. You are checking on a patient with diabetes and you go to examine his feet. When you gently lift the cover, you smell something malodorous and notice an area on his leg that you suspect is infected. You examine the area closely. The patient is not active so your differential diagnosis also includes a deep vein thrombosis (DVT; blood clot). The patient loves science and asks that you explain to him in detail why you think he has an infection in his leg and why it’s more likely than a DVT. A. Describe your expected exam findings (i.e. what would lead you to assume he has an infected area on his leg) B. Describe to the patient in detail why each of these findings suggests infection/inflammation C. Describe to the patient the series of events that occurs when a pathogen breaches the outer layer of skin and how this leads to the signs you’ve observed 3. You’re a nurse working in a busy primary care setting. Because the physician is short on time, patients often have questions after their appointment. This gives you the opportunity to share your knowledge and counsel patients on various health topics. Today, you have a patient who was offered and refused the COVID-19 vaccine. You decide to talk with the patient to try to understand and hopefully address their concerns so they will get vaccinated. The patient explains to you that she’s heard about people “getting really sick” after they get the vaccine. She says she’s afraid of getting COVID-19 from the vaccine and doesn’t want to get sick. She also says she doesn’t “even understand how the stupid shot will protect me”. After you acknowledge that her concerns are valid and ask to have a conversation with her addressing them you: A. Explain why people get “sick” after they get the vaccine. B. Explain why the patient cannot get COVID-19 from the vaccine (choose any formulation) C. Explain how the COVID-19 vaccine works, what type of immunity it induces, and how this is protective for patients (choose any formulation)
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