1. True or False Despite widespread use of CNS drugs, knowledge of these agents is limited. We are. Question
Answered step-by-step
Asked by studentsuccess420
1. True or False
Despite widespread use of CNS drugs, knowledge of these agents is limited. We are a long way from fully understanding both the CNS and the drugs used to affect it.
2. __________ drugs are able to most readily cross the blood-brain barrier?
3. It is theorized that the effects of CNS drugs taken chronically is probably due to ________ that occur in the brain in response to prolonged drug exposure.
4. Match the Parkinson’s diseases drug to the correct MOA.
Drugs:
Entacapone
Benztropine
Selegiline
Carbidopa
Levodopa
Pramipexole
amantadine
MOAs:
increases dopamine synthesis
dopamine receptor agonist
inhibits MAO-B
promotes dopamine release
blocks levodopa destruction
inhibits catechol-O-methyltransferase
blocks acetylcholine receptors
5. _______________ consumption should be spread throughout the day to limit this dietary component’s risk of decreasing the therapeutic response to levodopa.
6. What is a realistic outcome for a patient receiving drug therapy for Parkinson’s Disease?
Select one:
a. Absence of tremor
b. Reversal of neurodegeneration
c. Improved ability to perform ADL’s
d. normal gait
7. What is a benefit of use of risperidone and olanzapine for AD patients?
Select one:
a. Amplified effect of other drugs
b. Improved memory
c. Improved appetite
d. Decreased neuropsychiatric symptoms
8. Match true or false to the following questions about Alzheimer’s disease (AD)
a. High levels of the neurotransmitter acetylcholine are found in patients with AD
b. Drugs can be helpful in treating secondary effects of AD such as depression and incontinence
c. Current drug therapy for AD is not highly effective at relieving symptoms
d. A blood test can confirm the diagnosis of Alzheimer’s disease
e. Effects of drugs for AD are long-lasting
f. An early symptom of AD is loss of appetite
g. The American College of Physicians recommends trying a cholinesterase inhibitor in all patients with mild to moderate AD
h. The neuronal damage occurring with AD is irreversible
9. What is a benefit of use of risperidone and olanzapine for AD patients?
a. Amplified effect of other drugs
b. Improved memory
c. Improved appetite
d. Decreased neuropsychiatric symptoms
10. The nurse working with Alzheimer’s patients is reviewing the adverse effects of the cholinesterase inhibitor, donepezil, that the nurse is administering to patients. The nurse learns the adverse effects are basically related to an increase in parasympathetic stimulation. What interventions should the nurse plan to use to prevent a common adverse effect?
a.Providing mouth moisturizers for dry mouth
b.Assessing for symptoms of hyperglycemia
c. Ensuring adequate fluids to prevent dehydration from diarrhea
d. Monitoring liver function tests
11. Current drug therapy for Multiple Sclerosis can slow the disease process.
True
False
12. Current drug therapy for Multiple Sclerosis can cure the disease.
True
False
13. Research suggests initiation of multiple sclerosis is linked to genetic, environmental, and microbial factors.
True
False
14. High dose IV ______ are usually used for acute episodes/relapses of MS
15. _______ is the only disease modifying drug approved for progressive-relapsing MS
16. When caring for a patient receiving phenytoin, which assessment finding is a priority to report to the prescriber? (which of these findings represents a potentially dangerous outcome)
a. Excessive growth of gum tissue
b. Inadequate consumption of foods rich in calcium and vitamin D
c. Morbilliform-like rash
d. Continuous back and forth movements of the eyes
17. Generalized convulsive status epilepticus is considered a medical emergency and the first medication that should be administered because it will stop the seizures quickly is:
a. IV fosphenytoin
b. IV benzodiazepine like diazepam or lorazepam
c. an oral benzodiazepine like diazepam or lorazepam
d. oral phenytoin
18. Which of the following are mechanisms of action of antiepileptic drugs? (Select all that apply)
a. Inhibit the action of the neurotransmitter GABA
b. Impair influx of calcium in axon terminals to prevent transmitter release
c. Block the actions of glutamate at NMDA and AMPA receptor
d. Bind to sodium channels when they are in the inactive state
19. To prevent development of hypotension and bradycardia during IV administration of phenytoin, it should be administered no faster than 50 mg/minute. The patient has an order for a loading dose of 800 mg phenytoin IV. The nurse should infuse the medication over_____ minutes.
20. Patients who suffer from ______ have muscles that are continuously contracted and do not relax.
SCIENCE
HEALTH SCIENCE
NURSING
NSG 225
1. True or False Despite widespread use of CNS drugs, knowledge of these agents is limited. We are
